Aidong Wen Selected Research

lithospermate B

1/2014	Magnesium lithospermate B improves myocardial function and prevents simulated ischemia/reperfusion injury-induced H9c2 cardiomyocytes apoptosis through Akt-dependent pathway.
11/2013	Magnesium lithospermate B reduces myocardial ischemia/reperfusion injury in rats via regulating the inflammation response.
2/2013	Antioxidant properties of magnesium lithospermate B contribute to the cardioprotection against myocardial ischemia/reperfusion injury in vivo and in vitro.

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Aidong Wen Research Topics

Disease

19	Reperfusion Injury 12/2021 - 12/2012
13	Neoplasms (Cancer) 01/2022 - 12/2010
13	Infarction (Infarctions) 01/2021 - 12/2012
13	Ischemia 04/2019 - 12/2012
12	Myocardial Ischemia (Ischemic Heart Diseases) 12/2021 - 01/2013
11	Inflammation (Inflammations) 07/2021 - 12/2012
11	Brain Ischemia (Cerebral Ischemia) 01/2021 - 12/2012
6	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2021 - 12/2012
6	Wounds and Injuries (Trauma) 01/2021 - 01/2014
6	Pain (Aches) 01/2020 - 12/2012
5	Type 2 Diabetes Mellitus (MODY) 01/2021 - 12/2013
5	Fibrosis (Cirrhosis) 10/2020 - 08/2015
4	Ischemic Stroke 12/2020 - 09/2018
4	Myocardial Infarction 11/2017 - 06/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2013
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2021 - 04/2019
3	Vascular Diseases (Vascular Disease) 01/2020 - 01/2018
3	Stroke (Strokes) 12/2019 - 09/2014
3	Necrosis 11/2017 - 07/2016
3	Hyperglycemia 01/2017 - 01/2015
3	Diabetic Cardiomyopathies 01/2017 - 01/2015
3	Diabetes Mellitus 12/2015 - 01/2010
2	Brain Injuries (Brain Injury) 06/2021 - 01/2019
2	Colorectal Neoplasms (Colorectal Cancer) 11/2020 - 06/2015
2	Insulin Resistance 01/2020 - 12/2013
2	Neuralgia (Stump Neuralgia) 01/2020 - 01/2017
2	Ulcerative Colitis 01/2020 - 01/2016
2	Hyperalgesia 01/2020 - 02/2015
2	Sleep Deprivation 01/2020 - 01/2020
2	Rheumatic Diseases (Rheumatism) 01/2020 - 07/2015
2	Neuroinflammatory Diseases 02/2019 - 12/2018
2	Brain Edema (Cerebral Edema) 02/2019 - 01/2019
2	Sepsis (Septicemia) 01/2019 - 04/2014
2	Ulcer 12/2017 - 09/2007
2	Hypoxia (Hypoxemia) 11/2017 - 01/2013
2	Burns 11/2017 - 09/2015
2	Vascular Remodeling 10/2017 - 12/2016
2	Breast Neoplasms (Breast Cancer) 02/2016 - 08/2011
2	Infections 04/2014 - 12/2013
2	Neurologic Manifestations (Neurological Manifestations) 01/2014 - 12/2012
1	Osteoporosis 01/2022
1	Neuroblastoma 06/2021
1	COVID-19 01/2021
1	Pathologic Processes 01/2021

Drug/Important Bio-Agent (IBA)

11	AntioxidantsIBA 12/2019 - 01/2010
8	Pharmaceutical PreparationsIBA 01/2022 - 09/2007
8	Proteins (Proteins, Gene)FDA Link 10/2020 - 08/2015
7	Glucose (Dextrose)FDA LinkGeneric 12/2019 - 02/2013
6	Neuroprotective AgentsIBA 12/2019 - 12/2012
6	hydroxysafflor yellow AIBA 12/2019 - 09/2014
6	CytokinesIBA 02/2019 - 11/2013
5	3,4-dihydroxyphenyllactic acidIBA 12/2021 - 01/2013
5	SaponinsIBA 11/2020 - 01/2010
5	Oxygen (Dioxygen)IBA 12/2019 - 02/2013
4	chikusetsu saponin IVaIBA 01/2020 - 07/2015
4	EnzymesIBA 02/2019 - 01/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 01/2015
3	Huang QiIBA 01/2021 - 12/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 04/2017
3	Sirtuin 1IBA 01/2021 - 12/2015
3	protocatechualdehydeIBA 11/2019 - 06/2013
3	Ethanol (Ethyl Alcohol)IBA 12/2017 - 01/2016
3	Malondialdehyde (Propanedial)IBA 11/2017 - 02/2013
3	Superoxide DismutaseIBA 11/2017 - 02/2013
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 08/2017 - 06/2013
3	AcidsIBA 12/2016 - 01/2014
3	SodiumIBA 03/2016 - 02/2015
3	lithospermate BIBA 01/2014 - 02/2013
2	Carthamus tinctorius Honghua extractIBA 01/2021 - 09/2014
2	ameroidIBA 01/2021 - 11/2018
2	pregna-4,17-diene-3,16-dione (guggulsterone)IBA 12/2020 - 12/2018
2	ResveratrolIBA 01/2020 - 01/2014
2	PolyphenolsIBA 01/2020 - 01/2014
2	osthol (osthole)IBA 01/2020 - 01/2017
2	Blood Glucose (Blood Sugar)IBA 01/2020 - 05/2017
2	Biological ProductsIBA 01/2020 - 01/2020
2	BerberineIBA 01/2020 - 01/2014
2	Therapeutic UsesIBA 01/2020 - 04/2014
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2017
2	Phosphotransferases (Kinase)IBA 11/2019 - 08/2011
2	LigandsIBA 08/2019 - 02/2014
2	Analgesics (Analgesic Drugs)IBA 12/2017 - 01/2017
2	Alfentanil (Alfenta)FDA LinkGeneric 04/2017 - 02/2015
2	Formaldehyde (Formol)FDA Link 04/2017 - 02/2015
2	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 01/2017 - 01/2014
2	7,3'-dihydroxy-4'-methoxyisoflavoneIBA 01/2017 - 12/2012
2	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2016 - 08/2015
2	Interleukin-6 (Interleukin 6)IBA 08/2016 - 11/2013
2	Lapatinib (GW572016)FDA Link 02/2016 - 08/2011
2	MB Form Creatine KinaseIBA 06/2013 - 01/2013
1	Zoledronic Acid (Zometa)FDA Link 01/2022
1	Denosumab FDA Link 01/2022
1	rheinIBA 07/2021
1	N-Methylaspartate (NMDA)IBA 06/2021
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2021
1	guanxin shutongIBA 01/2021

Therapy/Procedure

8	Therapeutics 01/2020 - 12/2010
3	Chinese Traditional Medicine (Traditional Chinese Medicine) 04/2019 - 08/2016
3	Ligation 01/2019 - 06/2013
2	Drug Therapy (Chemotherapy) 01/2020 - 12/2010